This can be avoided by the subject not looking directly into the camera. A pre-flash strobe from the camera flash will cause the pupil to contract and the red eye reflex will not be seen. This is now available in most modern cameras as ‘red eye reduction’ feature.
Red eye reflex is seen more in children as they naturally have larger pupils — certain animals have a highly reflective surface under the retina giving them greater red eye reflex, that is why red eye reflex is sometimes called ‘cat eye reflex’.
Source: The Hindu